U of M, St. Jude partner to tackle Parkinson’s, depression

Patient care

By Matt DePoint

University of Minnesota researchers and St. Jude Medical are collaborating to treat some of the most challenging and debilitating movement and neuropsychiatric disorders using deep brain stimulation (DBS), a treatment which uses electrical current to directly stimulate parts of the brain. The project is part of MnDRIVE (Minnesota’s Discovery, Research and InnoVation Economy), a $36 million biennial investment by the state that aims to solve grand challenges in areas that align with Minnesota’s industries, including discoveries and treatments for brain conditions.

MnDRIVE’s ongoing partnership with industry leaders will help to achieve its goals for treatments of brain conditions through neuromodulation, a therapeutic intervention that modulates (or changes) the activity of brain circuits to decrease symptoms and improve function.

“We are excited to be collaborating with St. Jude Medical to identify new and better approaches to delivering DBS therapy for patients with Parkinson’s disease, including, for example, changes in how the pulsed electrical stimuli delivered to targets deep within the brain are patterned, or organized,” said Kenneth Baker, Ph.D., assistant professor of neurology at the University of Minnesota. “We hope not only to improve the direct response of the motor abnormalities to DBS, but also to improve patient care by reducing technological and surgical burdens, such as battery replacements.” Continue reading